Computational Modeling of Nanoparticle Targeted Drug Delivery

Abstract

By using nanotechnology for tailored medication delivery, nanomedicine has great promise as a medical application. Nevertheless, the intricate in vivo circulatory system and the microscopic size of nanoparticles make it very difficult to characterise the targeted distribution process of nanoparticles in a vascular environment. A number of computer models have been created to shed light on the targeted delivery process of nanoparticles and to assist in the design of nanoparticles for optimum delivery in order to make sense of such a complex system. In order to facilitate effective targeted distribution, this article goes over several computational techniques for mDodeleilvtehreednabnyoIpnagrteicnletadteol:ivery and nanoparticle design. From molecular level ligand-reaction dynamics to continuum vascular flow and particle Brownian adhesion dynamics, the modelling approach sUpsaenr covers it all. It is believed that computer simulation can optimise drug carrier design and forecast the vascular environment particular to each patient.[4]